Biodegradability is becoming a non-negotiable in product development, but testing for it is often slow, expensive, and difficult to scale. Aropha is changing that with a unique approach that combines AI-powered simulation and physical lab testing to make biodegradability assessments faster, more affordable and easier to integrate into R&D workflows.
We sat down with Kuan Huang, co-founder and CTO of Aropha, to learn how a chance project during his Ph.D. turned into a mission to transform biodegradability testing with AI, speed and accessibility.
Q: Let’s start at the beginning—how did you get into biodegradability testing?
Kuan Huang: It actually started in 2019 when I was a Ph.D. student at Case Western Reserve University. A personal care chemical company reached out that needed help testing the biodegradability of some new polymer samples. We were trained in the standard lab methods and could help; but as we got deeper, I realized how inefficient the whole process was. Testing was expensive, turnaround times were months long and access was limited. We followed all the right protocols, but it was clear why so few companies were using these tests despite growing pressure from regulators and customers.
That project planted the seed for Aropha. We asked: what if we could make biodegradability testing faster, cheaper and more accessible, without compromising on accuracy?
Q: What are some other common pain points you’ve seen companies face in biodegradability testing?
Kuan Huang: We often see R&D teams frustrated by long wait times, confusing test choices or limited access to technical support. For early-stage developers especially, it’s tough to justify the cost of a single test let alone several rounds of optimization. Most companies also have limited in-house lab capabilities or regulatory experience that make navigating biodegradation assessments difficult.
Q: How does Aropha solve the challenges of traditional biodegradation assessments?
Kuan Huang: We built Aropha from the ground up to rethink how biodegradability testing is done. We make it easier by offering a straightforward process, transparent pricing and technical consultations upfront. Typical labs have 8–12 week lead times just to start a test. We’ve streamlined our process so we can begin most studies within 1–2 weeks of receiving samples. Our lab offers GLP-compliant physical tests, but we also provide non-GLP screenings for when R&D teams just need quick directional data, so they’re not locked into expensive regulatory testing too soon.
However, what really sets us apart is our integration of AI. With our Aropha Console, companies can now screen hundreds of chemicals with our predictive model, ArophaAI, and then validate results through our physical lab. This hybrid approach can shorten development timelines by up to six months and cut testing costs by as much as 40%.
It’s helping R&D teams move faster and make better design decisions earlier in the process.
Q: What’s your role as Chief Technology Officer?
Kuan Huang: I lead our technology roadmap, which includes both the predictive modeling side and the lab testing systems. I also stay deeply involved in the science—we’re constantly validating and refining our models against physical test results. And because I come from an academic background, I make sure our methods stay rigorous and defensible, especially as customers use our data for regulatory submissions.
Q: What types of substances and formulations can Aropha’s lab test for biodegradability?
Kuan Huang: We support a broad range of substances, from well-defined small molecules to complex polymers, mixtures, emulsions, and even materials with proprietary or partially known structures. We frequently test surfactants, solvents, personal care actives, coatings, agrochemicals and biodegradable plastics. Our protocols are designed to handle both soluble and insoluble materials, and we’ve built in flexibility for tailoring methods based on material class, solubility or application.
Q: How can R&D teams ensure the accuracy and scientific rigor of biodegradation assessments?
Kuan Huang: All of our tests follow internationally validated methods with QA oversight, and our team is trained in method-specific protocols to reduce variability. We run tests under over 60 international standards, including OECD, ISO, ASTM and EPA guidelines. Common examples include OECD 301, OECD 302 and OECD 306, ISO 14855 for composting, and OECD 311 for anaerobic conditions. We’ve also implemented automations and other processes that optimize our lab for maximum efficiency, while ensuring quality results.
Accuracy and reproducibility are priorities; speed never comes at the expense of data quality.
Q: What would you say to companies that are hesitant about outsourcing environmental testing?
Kuan Huang: We want you to think of Aropha as an extension of your team. If you don’t have environmental testing lab space, instrumentation or regulatory staff, we’ll help with test selection, experimental design, and interpreting results. We’ve worked with many small and large companies who rely on us for both execution and guidance. We also provide regulatory support documentation and help connect results back to relevant claims or sustainability standards.
Also, if they’re unsure, start with a non-GLP screen. It’s a smart way to derisk and prioritize which materials are worth the regulatory investment of full GLP-compliant testing.
Q: What do you want R&D teams to know about the future of biodegradability testing?
Kuan Huang: Testing doesn’t have to be a bottleneck anymore. We’re at a point where you can make smart decisions earlier, whether you’re designing for eco-labels, regulatory compliance or internal sustainability goals. Our mission is to give R&D teams the tools to move fast without cutting corners.
Also, innovation in this space isn’t just about better lab tests, it’s about digitally transforming how testing fits into product development. That’s the future we’re building.